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Cortexolone 17a-propionate foda

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SKU: 19608-29-8. category:

AASraw yana tare da kira da kuma samar da damar daga gram zuwa tsari na kundin Cortexolone 17α-propionate foda (19608-29-8), ƙarƙashin tsarin CGMP da tsarin kula da kyawawan dabi'u.

Samfur Description

Cortexolone 17a-propionate foda video


Cortexolone 17a-propionate foda ainihin Maƙallan

name: Cortexolone 17a-propionate foda
CAS: 19608-29-8
Kwayoyin Formula: C24H34O5
Girman kwayoyin halitta: 402.52
Shawarwar Melt:
Ajiye Temp: Room Zazzabi
Color: White zuwa kashe-farin foda foda


Cortexolone 17a-propionate sake zagayowar

names

CAS: 19608-29-8
Sunaye masu suna: cortexolone-17a-propionate,
Sauran Sunaye: CB-03-01, Farin Ciki, Bodazula Foda, 11-deoxycortisol 17a-propionate, Cortexolone 17a-propionate foda

Cortexolone 17a-propionate Amfani

Cortexolone 17a-propionate wani aboki ne mai maganin cututtuka - mai mahimmanci, antagonist mai karɓan inrogene - wanda ke ci gaba da ci gaba ta hanyar Cassiopea da Intrepid Therapeutics don amfani da su a matsayin magani na magani a cikin maganin yanayin da ke dogara da inrogene ciki har da acne vulgaris da kuma asrogenic alopecia asara gashi).

Mene ne sashin Cortexolone 17α-propionate

Cortexolone 17a-propionate 1% cream, wani sabon yiwuwar antiandrogen domin magani na maganin ciwon hauka vulgaris. Wani matukin jirgi wanda aka ƙaddamar da shi, wanda yake da sau biyu a cikin binciken vs. placebo da tninoin 0 · 05% cream.

Fage

Acne vulgaris wani ɓangare ne na ɓangaren mai kula da jigilar kamfanoni wanda mahaukacin da ke taimakawa wajen farawa da kuma jurewa. Amfani da antiandrogens shine sabili da tasiri; Duk da haka, antiandrogens don amfani da akasarin ba samuwa a kasuwa. Cortexolone 17a-propionate wani sabon abu ne wanda ke iya amfani da shi a cikin ƙwayoyin cuta.

BAYANNI

Don kimanta kariya da kwarewa na musamman na Cortexolone 17α-propionate 1% cream a acne vulgaris idan aka kwatanta da placebo kuma tare da 0 · 05% cream na tretinoin.

MODANE

Mutum saba'in da bakwai tare da fatar ido na fuskoki sun zana 2-3 bisa ga binciken mai bincike (IGA) da aka bazu don karɓar cream na placebo (n = 15), ko kuma Cortexolone 17a-propionate 1% cream (n = 30), ko 0 05 tretinoin % cream (n = 32) sau ɗaya a rana a lokacin kwanta barci don 8 makonni. An yi amfani da inganci na asibiti a kowane mako na 2 ciki har da ƙididdigar launi (TLC), ƙididdigar kututtuka na ƙwayoyin cuta (ILC), alamar ƙwayoyin cuta (ASI) da IGA. Kariyar tsaro ya ƙunshi cibiyoyin kulawa da gida, gwaje-gwajen gwaje-gwaje, jarrabawa jiki, alamu masu muhimmanci da rikodi na abubuwan da suka faru.

Sakamakon

An adana magungunan CB-03-01 sosai, kuma ya kasance mafi kyau fiye da placebo game da TLC (P = 0 · 0017), ILC (P = 0 · 0134) da ASI (P = 0 · 0090), kuma ya fi tasiri sosai fiye da gwada. Wannan samfurin ya haifar da nasarar samun nasarar 50% a dukkanin sigogi na sama. CB-03-01

karshe

Wannan binciken na gwajin ne na goyan bayan abin da ake amfani dashi don amfani da magungunan antiandrogens a cikin maganin ciwon hauka. Cortexolone 17a-propionate 1% cream yana ganin ya dace tare da bayanin manufa mai amfani da antiandrogen don amfani da akasarin.

Yadda Cortexolone 17α-propionate ke aiki

Cortexolone 17a-propionate (CAS 19608-29-8), ko 11-deoxycortisol 17α-propionate, wani maganin steroidal antiandrogen - musamman, antagonist mai karɓa na asrogen - wanda ke ci gaba da ci gaba ta hanyar Cassiopea da Intraid Therapeutics don amfani da su a matsayin magani a cikin jiyya na yanayin da ake dogara da inrogene ciki har da acne vulgaris da kuma asrogenic alopecia (asalin gashin gashi). Ita ce C17a propionate Ester na 11-deoxycortisol (cortexolone); An gano C17a esters na 11-deoxycortisol don samun aikin antiandrogen, kuma an zabi 17A-propionate na cortexolone don ci gaba bisa ga tushen maganin likitanci mafi kyau.

A cikin berayen, an samo miyagun ƙwayoyi don ya sami aiki mai ƙarfi mai ƙarfi, amma aikin rashin aiki na antiandrogen wanda ba zai yiwu ba yayin da ake gudanar da shi ta hanyar allurar cututtukan. Bugu da ƙari, cortexolone 17α-propionate ba progonadotropic, yana nuna cewa yana da zafin jiki. A cikin kwayar halitta, magungunan maganin miyagun ƙwayoyi ya fi girma daga na progesterone, flutamide, da finasteride kuma ya kasance daidai da na cyproterone acetate.

Wani gwajin gwajin gwajin gwaji a 2011 na maza da aka bi da Xteu-X-X-X-X-X-X-X-X-X-X-X-X-X-X-X-X-X-X-X-X-X-X-X-X-X-X-X-X-X-X-NHXX Bugu da ƙari kuma, tasirinta ya fi girma fiye da na mai aiki mai kirkiro, 17% cream na tretinoin. Kamar yadda na 1, miyagun ƙwayoyi yana cikin gwaji na gwaje-gwaje na III don ƙwayoyin cuta da ƙananan ƙwayoyin cuta na II da gwagwarmaya.

Gargadi

Cortexolone 17a-proprionate, Breezula foda a cikin siffofin polymorphic: na farko dangi na dangi, wanda ya ƙare a Amurka a 2022 / 23 da kuma a 2022 a sauran duniya, ya rufe aikin likita na fili don maganin kuraje, alopecia da wasu cututtuka; mahaifa na biyu sune rufe dukkanin siffofin crystalline na API, abubuwan da ke dauke da API guda daya da kuma aikin likita da suka shafi likitanci, AGA da sauran cututtuka: an riga an riga an kawo wannan dangi a Amurka, Turai, Kanada, Japan da kuma wasu ƙasashe, za su ƙare a 2030 a Amurka da 2028 a sauran duniya.Breezula foda

Cortexolone 17a-propionate Raw Foda

Min umarni 10grams.
Za'a iya aika da binciken akan al'ada yawa (A cikin 1kg) a cikin 12 hours bayan biya.
Don yin umurni mai girma zai iya aikawa a cikin kwanakin 3 aiki bayan biya.

Cortexolone 17a-propionate Maganin Foda Cike

Don bincika Abokin Abokin Abokanmu (CSR) don cikakkun bayanai, don ƙudurinka.Winlevi foda

Cortexolone 17a-propionate Marketing

Da za a bayar da shi a nan gaba.

Shin Cortexolone 17α-propionate Shin Dukkan Hanya

Cortexolone 17a-propionate ne sabon steroidal-ester, mai tsinkaye mai siffar androgen-antagonist, wanda ke da nauyin aikin maganin antiinflammatory, wanda ya fi dacewa don maganin maganin hawan fata. CB-03-01 yana aiki a matakin ɗan adam mai karɓar nau'in-kwayoyin halitta ba tare da hana 5a-reductase a cikin fata ba. Jirgin sanyi zai iya shiga jikin fata na mutum kuma an gaggauta inganta shi zuwa iyayen mahaifi na mahaifa wanda ba shi da tasiri. Mafi mahimmanci, har zuwa yau, bai nuna duk wani tasiri na ɓangaren ƙwayar cuta na gida ko na tsarin.


Yadda zaka saya Cortexolone 17a-propionate foda daga AASraw

1.To tuntube mu ta hanyar imel ɗinmu tsarin bincike, ko skypewakilin sabis na abokin ciniki (CSR).
2.To samar mana da tambaya da adireshinka.
3.Our CSR zai ba ka zance, lokacin biya, lambar ƙididdiga, hanyoyin bayardawa da kuma kwanan wata zuwa ranar da aka zo (ETA).
4.Bayayyar da aka yi kuma za'a fitar da kayayyaki a cikin 12 hours (Domin a cikin 10kg).
5.Goods samu da bada comments.


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COA

HNMR

Recipes

Cortexolone 17a-propionate Rashin Mafallin Furo:

Don bincika Abokin Abokin Abokanmu (CSR) don cikakkun bayanai, don ƙudurinka.Winlevi foda

Karin bayani & amsoshin samfurin

Kyauta mafi kyau na gashi ga maza: Cortexolone 17α-propionate foda (CB-03-01)