Nootropic Coluracetam: Yadda Ake Aiki a kan Brain da Kula da Tashin hankali
AASraw yana samar da NMN da NRC foda a cikin girma!

Coluracetam

Gidan Racetam na Nootropic– Coluracetam

Coluracetam (BCI-540, ko MKC-231) shine nootropic mai narkewa mai ƙanshi a cikin rukunin racetam na mahaɗan. Coluracetam ya fi ƙarfin gaske fiye da asalin racetam, Piracetam. Coluracetam ya sami izinin mallakar Mitsubishi Tanabe Pharma na Japan a cikin 2005. Yin shi ɗaya daga cikin sababbin ƙwayoyin ƙwayoyin ƙwayoyin ƙwayoyin cuta.

An sayar da haƙƙin mallaka na Coluracetam zuwa BrainCells, Inc. a San Diego, California. BrainCells wani ƙaramin kamfani ne mai sarrafa kansa wanda ke da ƙwarewa wajen haɓaka mahaɗan don magance babban cututtukan ciki (MDD), rashin jin daɗin jiyya (TRD), da cutar Alzheimer.

Coluracetam yayi kama da tsarin Piracetam. Kuma kamar kowane nau'in racetam nootropics, yana da ƙwayar pyrrolidone a ainihinsa. Binciken bincike na asibiti na baya-bayan nan yana nuna yuwuwar magance cututtukan ciki, da kuma cutar jijiyoyin gani da ido.

Coluracetam yana da ƙarfi sosai choline niyya supplement. Yana boosts kwakwalwarka 's choline hira da acetylcholine (ach) ta hanyar babban dangantaka choline fahimta (HACU) tsari. Wanne yana ƙara faɗakarwa, mai da hankali ga daki-daki da ƙwaƙwalwa.

Wasu bincike, da ƙwarewar mutum suna nuna Coluracetam na iya shafar masu karɓar AMPA. Yin shi mai yuwuwar ampakine nootropic. Wanne zai iya bayyana abubuwan da ke kama da motsa jiki ba tare da tasirin abubuwan kara kuzari na gargajiya ba. Har ila yau, Coluracetam yana nuna wasu halayen damuwa (anti-tashin hankali) na taimakawa inganta yanayi da nutsuwa cikin damuwa.

 

Yaya Coluracetam Works(Hanyar Aiki)

Kamar yawancin mahaɗan racetam, coluracetam (CAS:135463-81-9) yana aiki akasari ta hanyar ƙaruwa matakan neurotransmitter acetylcholine, wanda ke da alaƙa da ilmantarwa, ƙwaƙwalwar ajiya, da kuma cognition.

Koyaya, hanyar da coluracetam ke tsara matakan acetylcholine na musamman ne. Yawanci, racetams yana haifar da samar da acetylcholine ta hanyar motsa masu karɓa masu dacewa, amma coluracetam yana yin hakan ta haɓaka haɓakar ƙawancen haɗin kai, ko HACU. Tsarin HACU yana ƙayyade ƙimar da aka shigar da choline a cikin jijiyoyi don canzawa zuwa acetylcholine.

Ta hanyar kara yawan abin da choline ke shiga cikin jijiyoyin jijiyoyi, coluracetam yana inganta samar da acetylcholine kuma yana haifar da matakan kwakwalwa na wannan mahimmin sakon kwayar tashi. zuwa ga saurin wadatar choline don ɗauka.

Tare waɗannan ayyukan suna haifar da manyan matakan acetylcholine, waɗanda ke haɗuwa da haɓaka haɓaka da ƙwaƙwalwa.

Coluracetam

amfanin kuma effects Of Coluracetam

 Coluracetam Yana Inganta orywaƙwalwar ajiya da Ilmantarwa

Fa'idodin Coluracetam ya tabbatar da aiki a cikin aiwatar da aiki da hankali da ƙwaƙwalwar ajiya a cikin beraye da irin wannan tasirin akan mutane. Brain Cells Inc. sun gudanar da wani bincike wanda ya nuna ci gaban hankali a cikin beraye bayan karbar AF64A na tsawon kwana takwas. Ci gaban ya ci gaba da ɗorewa har ma fiye da magani. Alzheimer ta cutar yana haifar da ƙananan matakan acetylcholine. Ta hanyar girma acetylcholine a cikin hippocampus, coluracetam zai haɓaka alamun cutar Alzheimer kamar rikicewar ilmantarwa da ƙarancin ƙwaƙwalwar ajiya.

 

 Coluracetam Yana Rage Jiyya-Rashin Jituwa

A cikin nazarin mutane 101 da ke da baƙin ciki, waɗanda ba su sami sakamako tare da magungunan antidepressants ba, yana da tasiri mai tasiri kan bayyanar ingantaccen rayuwa a 80 MG sau 3 a rana. Koyaya, wannan shine kawai binciken akan mutane. Capacityarfin da yake da shi don rage girman damuwa na iya zama abin dogaro saboda tasirinsa mai kyau a cikin maganin ɓacin rai.

 

 Coluracetam Yana Rage Damuwa

A cikin nazarin bera, yin amfani da kwanakin 21 na coluracetam yana nuna ci gaba na 20% a cikin damuwa, wanda ya fi girma fiye da tasirin 12% na tasirin valium a cikin kashi ɗaya a cikin wannan binciken.

 

 Coluracetam Yana inganta Neurogenesis

Wasu nazarin sun ambaci cewa yana taimakawa tare da neurogenesis. Babbar hanyar har yanzu ba ta bayyana ba, amma tana da nasaba da yadda ake gudanar da ita tsawon makonni, wanda hakan ke karuwa a cikin acetylcholine a cikin yankin hippocampus. '' Ba a san ma'anar ba, amma ana tunanin yana da alaƙa da ƙaruwa a cikin hippocampal acetylcholine lokacin da ake ɗora coluracetam kowace rana don 'yan makonni.

 

 Coluracetam Yana taimakawa tare da Schizophrenia

Coluracetam yana haɓaka aikin ChAT a cikin berayen tare da lalata kwayar jijiyoyin. Wannan haɓaka ya nuna yana iya amfanar da marasa lafiya da cutar ta ɓacin rai ta hanyar wannan kwayar ta enzyme. Researcharin bincike kai tsaye kan mutanen da ke fama da cutar ƙwaƙwalwa tana gudana.

 

 Coluracetam Inganta Gani

Coluracetam ya nuna ƙarfin gani kamar haɓaka ingantaccen launi, hangen nesa, da haske. Musamman, yana inganta ci gaban jijiya don cututtukan cututtukan cututtukan zuciya. Yawancin karatu sun ambaci mafi kyawun hangen nesa da kaifin gani, amma babu wani binciken kimiyya da ya tabbatar da wannan tasirin.

AASraw shine ƙwararren masanin masana'antar Coluracetam.

Da fatan za a danna nan don bayanin zance: Saduwa da mu

 

Ta yaya Coluracetam ke aiki a cikin Brain?

Coluracetam yana haɓaka lafiyar kwakwalwa da aiki ta hanyoyi da yawa. Amma biyu musamman sun fice.

Coluracetam yana inganta kwakwalwarka's ɗaukar hoto ta hanyar niyya da aiki tare da aiwatar da haɗin gwiwa mai ƙarfi (HACU) a cikin ƙwayoyin kwakwalwa.

Acetylcholine (ACh) ya kunshi choline da acetate. Wadannan dole ne su kasance zuwa tashar neuron a kowane lokaci. Don haka za'a iya hada ACh a duk lokacin da ake buƙata.

Kyautattun layi da ke yawo a cikin jini yana keta shingen kwakwalwa-jini. Kuma an ɗauke shi ta ƙananan ƙananan ƙananan ƙwayoyin cuta. Ana ɗaukar shi zuwa cikin neuron ta tsarin haɗin haɗin haɗin gwiwa mai ƙarfi (HACU). Yin kira na ACh yana faruwa a cikin ɓoye na synaptic. Sarari tsakanin jijiyoyi yayin tafiya a cikin jijiyar.

Tsarin HACU ya dogara ne da zazzabi-, kuzari-, kuma ya dogara da sodium. Wannan tsarin shine ainihin hanyar da ake buƙatar choline da ake kira na ACh zuwa cikin neuron. Kuma wannan shine matakin takaita yawan kudi wajen kera wannan babbar kwayar cuta mai daukar hankali.Lokacin da wannan tsarin ya lalace ko yayi aiki ba kamar yadda aka tsara shi ba, zaka sami matsala da ƙwaƙwalwa, koyo, da kuma hazowar ƙwaƙwalwa.

Coluracetam yana haifar da wannan aikin kuma yana taimaka masa aiki sosai. A zahiri, da alama yana haɓaka aikin HACU. Ko da a cikin jijiyoyin da suka lalace. Acara yawan acetylcholine a cikin ƙananan ƙwayoyin cuta yana taimaka inganta ƙwaƙwalwar ajiya, haɓaka cognition kuma yana ba da damar yanke shawara mafi kyau.

Hakanan Coluracetam yana inganta ingantaccen AMPA. Masu karɓar AMPA suna shafan glutamate. Wanne ke aiki a cikin kwakwalwa da kuma tsarin kulawa na tsakiya don haɓaka faɗakarwa da faɗakarwa.

Coluracetam yana aiki tare da ƙarfin AMPA da haɓaka haɓakar haɓaka. Wannan haɗin yana da alama yana taimakawa inganta rikicewar yanayi ba tare da tasirin matakan serotonin ba.

Serotonin Masu Zaɓuɓɓukan Zaɓuɓɓukan Zaɓuɓɓuka (SSRIs) ita ce hanyar likita ta yau da kullun da aka fi dacewa don magance rikicewar yanayi da damuwa. Sun zo tare da jerin abubuwan illa masu illa. Kuma ba ku aiki ga kowane mai haƙuri da ke baƙin ciki.

Masu bincike sun ba da rahoton cewa Coluracetam na da amfani wajen magance babbar matsalar rashin lafiya da rashin damuwa. Ba tare da tasirin matakan serotonin a cikin kwakwalwa ba. Kuma ba tare da tasirin da ke tattare da lalata serotonin ba.

Coluracetam

Coluracetam Amfani: Sashi Kuma Matsayi Don Nunawa Kawai

Coluracetam wani fili ne wanda ba a samun sa a kowane abinci kuma jikin mu ba zai iya samar da shi ba. Saboda haka, hanya guda daya tak wacce za'a samar da amfanin wannan kwayar ta hanyar kari.

Coluracetam yawanci ana siyar dashi a foda ko sifofin capsule kuma ana iya ɗaukar shi da baki. Hakanan za'a iya ɗaukar ƙwayoyi sublingually (ƙarƙashin harshe) don saurin sha da sauri.

Tunda coluracetam wakili ne mai ƙarfi musamman, yana da kyau a fara da mafi ƙarancin sakamako. Idan kun ga kuna buƙatar ƙara yawan maganin don jin fa'idodi, ya kamata a yi haka a hankali kuma kada ya wuce 80mg.

Coluracetam ba mai guba ba ne kuma ana ɗaukar sahihi kuma mai jurewa sosai.Kusan ƙananan illolin da ke tattare da mahaɗan, kamar damuwa, ciwon kai, gajiya da tashin zuciya. Wadannan cututtukan suna da wuya kuma yawanci suna faruwa ne kawai lokacin da babu wadataccen madaidaicin madauri na choline da za'a yi amfani dashi don kira na acetylcholine. Wannan shine dalilin da ya sa muke ba da shawarar fara haɓaka-haɓaka coluracetam tare da haɓaka haɓakar ƙira kamar citicoline.

Coluracetam na iya hulɗa tare da wasu magunguna, musamman waɗanda ke hulɗa tare da mai karɓar NMDA. Wannan ya hada da masu hana maganin tari da maganin sa maye. Sauran abubuwan da suke hulɗa tare da tsarin cholinergic, kamar maganin glaucoma da nicotine, na iya yin hulɗa tare da tasirin coluracetam. Coluracetam na iya magance tasirin magungunan anti-cholinergic (kamar wasu Benadryl, wasu antipsychotics da magungunan Parkinson).

Kamar yadda yake tare da kowane ƙarin, idan kuna shan magani ko kuna da yanayin lafiya, yana da kyau kuyi magana da likitanku kafin fara kowane kari tsarin mulki.

 

 How To stacks Well With Sauran Magunguna

Coluracetam kwaya ce mai narkewa mai narkewa, saboda haka ta fi dacewa da kitsen mai mai lafiya irin su kwakwa ko man MCT.

Coluracetam shima yakamata a sanyashi tare da karin kariya kamar su citicoline. Citicoline yana ƙara yawan wadatar da ke akwai don kira. Tsarin zai iya haifar da sakamako mai karfi ta hanyar kara wadatar da ake samu (citicoline) da ikon hada shi cikin acetylcholine (coluracetam).

 

 Shawarwarin seari: 5-80mg kowace rana

Muna bada shawara tsakanin 5-80mg na coluracetam kowace rana.

Iyakar haɗarin haɗarin haɗari na coluracetam shine 80mg kowace rana. Koyaya, muna ba da shawarar kasancewa tare da 35mg kowace rana saboda sakamakon ƙananan allurai ba a riga an bincika su cikin mutane ba.

Zai fi kyau a raba waɗannan allurai zuwa kashi na safe ko na rana. Misali, kashi 20mg na 10mg da safe da kuma karin 10mg da rana.

Kamar yadda aka ambata a baya, ya kamata ku fara a ƙarshen ƙarshen sikelin dosing. Farawa daga mafi ƙarancin tasiri mai tasiri zai rage yiwuwar fuskantar duk wata illa mara kyau.

 

Coluracetam Side Gurbin

Coluracetam ba mai guba ba ne. Don haka ana ɗaukarsa mai haƙuri da aminci. Yawancin masu amfani da farko na Coluracetam suna ba da rahoton gajiya wanda yawanci sakamakon farawa ne da maɗaukakiyar kwaya.

Ka tuna, Coluracetam yana aiki ta haɓaka haɓakar choline a cikin kwakwalwarka. Choline shine mai gabatarwa ga samar da acetylcholine. Idan babu wadatar choline a cikin tsarin ku, zaku ji illar.

Hanyoyi masu ban sha'awa suna da wuya amma zasu iya haɗa da tashin hankali, gajiya, ciwon kai, jin tsoro da tashin hankali. Bugu da ƙari, sakamakon lalacewa yana haifar da sababbin asali na nootropic.

Ciwon kai daga amfani da Coluracetam yawanci yakan faru yayin da ka manta ka haɗa shi tare da kyakkyawan kari mai kyau. Ciwon kai yawanci alama ce ta raunin ƙugu a cikin kwakwalwarka.

 

Bayani - Coluracetam

Coluracetam shine ɗayan sabbin membobin rukunin racetam nootropics, amma abin so ne tare da yawancin masu amfani.

Yana ƙara matakan `` neurotransmitter na koyo '' acetylcholine, wanda zai iya haɓaka haɓaka, kuma nazarin dabba ya nuna cewa zai iya daidaita ƙarancin ƙwaƙwalwar ajiya ba tare da mahimman sakamako ba. Kodayake akwai ɗan binciken rubuce-rubucen ɗan adam game da coluracetam, nazarin da ake yi yana nuna cewa yana iya zama magani mai mahimmanci don damuwa da damuwa.

Yawancin masu amfani suna dogaro da shi azaman ɗaga abin ɗorewa da haɓaka haɓakar ƙwaƙwalwar ajiya wanda ke ba su kyakkyawar kulawa da nutsuwa. Wasu kuma sun ce yana ba su kwatankwacin “hangen nesa na HD”, yana mai da launuka haske, bambanci ya fi tsanani, kuma hasken ya fi haske.

Coluracetam abu ne mai tasiri, saboda haka yawan adadin ya yi ƙasa, kuma an san shi mai saurin aiki. Ana siyar dashi azaman abincin abincin kari a cikin Amurka kuma ana iya shigo da doka ta cikin Kanada da Burtaniya cikin ƙananan kuɗi.

Akwai sauran abubuwa da yawa da za a koya game da coluracetam, amma yana da aminci ga mafi yawan masu amfani idan aka ɗauke su da gaskiya. Idan kuna sha'awar ƙara sabon abu daban da na ku nootropic tari, coluracetam na iya zama ɗaya don la'akari.

Coluracetam bashi da yawan bincike, karatun da ake dasu yana nuna babbar damar amfani dashi. Yana ɗayan ɗayan rikice-rikice masu rikice-rikice na yau da kullun, gefe da gefe tare Fasoracetam. Koyaya, kwanan nan, FDA ta amince da wani "ingantaccen" nau'i na Fasoracetam don maganin ADHD.

AASraw shine ƙwararren masanin masana'antar Coluracetam.

Da fatan za a danna nan don bayanin zance: Saduwa da mu

 

reference

[1] Brauser D. "Magungunan Neurogenesis masu motsa hankali suna Nuna Alkawari game da Kula da Babban Rashin Tunawa" Labaran Kiwon Lafiya na Medscape Satumba 21, 2009

[2] Murai S., Saito H., Abe E., Masuda Y., Odashima J., Itoh T. Journal of Neural Transmission General Sashe. 231; 1994 (98): 1-1.

[3] Takashina K., Bessho T., Mori R., Eguchi J., Saito K. "MKC-231, mai haɓaka haɓakar haɓakawa: (2) Tasiri kan kira da kuma sakin acetylcholine a cikin berayen da aka kula da AF64A." Journal of Neural Transmission (Vienna). 2008 Jul; 115 (7): 1027-35.

[4] Bessho T., Takashina K., Eguchi J., Komatsu T., Saito K. "MKC-231, mai haɓaka haɓaka-haɓaka: (1) ci gaba mai ɗorewa na dogon lokaci bayan sake gudanar da mulki a cikin berayen da aka kula da AF64A." Journal of Neural Transmission (Vienna). 2008 Jul; 115 (7): 1019-25.

[5] Akaike A., Maeda T., Kaneko S., Tamura Y. Jaridar Jafananci na Ilimin Magunguna. 231 Feb; 1998 (76): 2-219

[6] Shirayama Y, Yamamoto A, Nishimura T, Katayama S, Kawahara R (Satumba 2007). "Bayyanarwar da ta biyo baya ga mai dauke da kwaya mai kara MKC-231 yana haifar da nakasuwar halayyar halayyar phencyclidine da kuma raguwar jijiyoyin da ke cikin beraye". Turai Neuropsychopharmacology. 17 (9): 616–26.

[7] Gudanar da Ayyukan Gano Lafiya na Ba da Agaji don Jihar California, IRS.gov.

[8] Malykh, AG, & Sadaie, MR (2010). Piracetam da Piracetam-Kamar Magunguna. Magunguna, 70 (3), 287-312.

0 Likes
182 Views

Za ka iya kuma son

Comments an rufe.