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Trilostane foda (13647-35-3)

Rating: SKU: 13647-35-3. category:

AASraw yana tare da haɓakawa da ikon samarwa daga gram zuwa adadin taro na Trilostane foda (13647-35-3), ƙarƙashin ƙididdigar CGMP da tsarin kula da inganci mai kyau.

Samfur Description

Trilostane foda (13647-35-3) bidiyo


Trilostane foda (13647-35-3) Specification:

Tsarin Kemikal: Product Name: Trilostane
CAS No.: 13647-35-3
kwayoyin Formula: C20H27NO3
kwayoyin Weight: 329.43
Standard: In-house
Storage: Dry, duhu da 0 - 4 C don gajeren lokaci (kwanaki zuwa makonni) ko -20 C na dogon lokaci (watanni zuwa shekaru).
Takaddun (COA & HPLC da sauransu): Ya Rasu

Trilostane foda (13647-35-3) Dlakabi:

Trilostane foda shine inhibitor na 3β-hydroxysteroid dehydrogenase wanda aka yi amfani dashi don maganin cututtukan Cushing da hyperaldosteronism na farko. Wadannan sune rikice-rikice guda biyu inda aka samar da adadin ƙwayoyin jijiya na corticosteroid a cikin jiki. Corticosteroids suna da mahimmanci ga jiki don yin amfani da carbohydrates, fats da sunadarai kuma don amsawa ta al'ada ga damuwa. Hakanan suna da mahimmanci don tsarin gishirin da daidaita ma'aunin ruwa a jiki. Trilostane foda yana taimakawa hana samar da corticosteroids, sarrafa alamun da ke hade da waɗannan rikice-rikice.

Trilostane foda kuma na iya zama da amfani a lura da cutar kansa wanda ya sake faruwa a cikin matan da suka shuɗe.

An amince da shi kwanan nan a cikin 2008 don maganin cutar Cushing (hyperandrenocorticism) a cikin karnuka. Hakanan magani na farko da aka amince dashi don maganin duka dabbobin Cushing na pituitary-da na adrenal-a cikin karnuka. Wannan ƙwayar magunguna yana aiki ta hanyar dakatar da samar da cortisol a cikin gland na adrenal.

reference:

  • 1: Midence JN, Drobatz KJ, Hess RS. Magungunan Cortisol a cikin Dogs ɗin da aka kayyade tare da magance Hyperadrenocorticism tare da Trilostane. J Vet Intern Med. 2015 Nuwamba; 29 (6): 1529-33. doi: 10.1111 / jvim.13615. Epub 2015 Sep 16. Buga PMID: 26374943.
  • 2: Fracassi F, Corradini S, Floriano D, Boari A, Aste G, Pietra M, Bergamini PF, Dondi F. Abubuwan haɓakawa don rayuwa a cikin karnuka tare da maganin hypercortisolism wanda aka bi da su tare da trilostane. Vet Rec. 2015 Jan 10; 176 (2): 49. doi: 10.1136 / vr.102546. Epub 2014 Aug 28. PubMed PMID: 25170036.
  • 3: Bonadio CM, Feldman EC, Cohen TA, Kass PH. Kwatantawa da sakamakon gwajin motsa jiki na adrenocorticotropic ya fara ne 2 awanni 4 bayan gudanarwar trilostane a cikin karnuka tare da dabi'un dabi'a na hyperadrenocorticism. J Vet Intern Med. 2014 Jul-Aug; 28 (4): 1239-43. doi: 10.1111 / jvim.12357. Epub 2014 Mayu 26. Wanda aka buga PMID: 24863172.

BATSA DA TATTAUNAWA:

Ana Samun Wannan Abubuwan ne Don Amfani da Bincike Kawai. Sharuɗɗan Siyarwa suna Aiwatarwa. Ba don Amfani da Dan Adam bane, ko Likita, dabbobi, ko Amfani na Gida.


COA

HNMR

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