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Nicotinamide riboside chloride

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Samfur Description

Abubuwa Na Asali

Product Name Nicotinamide riboside chloride
CAS Number 23111-00-4
kwayoyin Formula C11H15ClN2O5
Formula Weight 290.7
nufin abu ɗaya ne 23111-00-4

Nicotinamide riboside chloride

Nicotinamide riboside (chloride)

3-Carbamoyl-1-((2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium chloride

Nicotinamide ribose chloride

Appearance White foda
Ajiye da kulawa 0 - 4 C don gajere (kwanaki zuwa makonni), ko -20 C na dogon lokaci (watanni).

 

Nicotinamide riboside chloride Bayani

Nicotinamide Riboside Chloride (NIAGEN) shine nau'in gishirin chloride na nicotinamide riboside (NR) .NR wani sabon nau'i ne na pyridine-nucleoside na bitamin B3 wanda ke aiki azaman kamfani na nicotinamide adenine dinucleotide (NAD) ko NAD + .NIAGEN gabaɗaya an amince dashi lafiya (GRAS) a Amurka don amfani dashi a cikin kayan abinci. Nicotinamide riboside chloride sigar lu'ulu'u ce ta Nicotinamide riboside (NR) chloride. Nicotinamide riboside chloride yana ƙaruwa matakan NAD [+] kuma yana kunna SIRT1 da SIRT3, yana ƙare a cikin haɓakar haɓakar haɓakar ƙwayar cuta da kuma kariya daga ƙoshin abinci mai ƙarancin abinci wanda ya haifar da rashin daidaituwa ta rayuwa. Nicotinamide riboside chloride foda ana amfani dashi a cikin abincin abincin.

 

Nicotinamide riboside chloride Mechanism na Aiki

Nicotinamide Riboside Chloride (NIAGEN) shine nau'in gishirin chloride na nicotinamide riboside (NR). NR shine nau'in pyridine-nucleoside na bitamin B3 wanda ke aiki azaman takaddama ga adenine dinucleotide ko NAD + na nicotinamide. NR yana lalata lalacewar ƙananan ƙwayoyin ganglion ƙananan ƙwayoyi ex vivo kuma yana kare kariya daga raunin ji a cikin ƙwayoyin beraye. Nicotinamide riboside foda yana hana tsoka, jijiyoyin jiki da melanocyte kara kwayar cutar kwayar halitta. Beenara yawan sabuntawar muscular a cikin beraye an lura da shi bayan jiyya tare da nicotinamide riboside, wanda ke haifar da jita-jita cewa zai iya inganta sabunta halittar gabobi kamar hanta, koda, da zuciya. Nicotinamide riboside kuma yana rage glucose na jini da hanta mai kiba a cikin prediabetic da kuma buga nau'ikan ciwon sukari na 2 yayin hana ci gaban cututtukan cututtukan cututtukan sukari. Lura: Nicotinamide Riboside chloride shine cakuda α / β.

 

Nicotinamide riboside chloride Aikace-aikace

Nicotinamide riboside chloride foda an rajista tare da lambar CAS 23111‐00‐4 da lambar EC 807‐820‐5. Sunan ta IUPAC shine 1 - [(2R, 3R, 4S, 5R) ‐3,4 ‐ dihydroxy ‐ 5‐ (hydroxymethyl) oxolan ‐ 2 ‐ yl] pyridin ‐ 1 ‐ ium ‐ 3 ‐ carboxamide; chloride. Tsarin kwayoyin na nicotinamide riboside chloride shine C11H15N2O5Cl, kuma nauyin kwayoyin 290.7 g / mol. Nicotinamide Riboside Chloride (NIAGEN) shine nau'in gishirin chloride na nicotinamide riboside (NR) .NR wani sabon nau'i ne na pyridine-nucleoside na bitamin B3 wanda ke aiki a matsayin share fage na nicotinamide adenine dinucleotide (NAD) ko NAD +. Jiki yana buƙatar NAD + don aiki koyaushe. Levelsananan matakan NAD + na iya haifar da matsalolin likita. Nicaukar riboside na nicotinamide na iya taimakawa ɗaga waɗannan ƙananan matakan NAD +.

 

amfanin Nicotinamide riboside chloride

Nicotinamide riboside Chloride, mai aiki da NAD + precursor, yana ƙaruwa matakan NAD + kuma yana kunna SIRT1 da SIRT3. Nicotinamide riboside Chloride foda shine tushen bitamin B3 (niacin) kuma amfani da Nicotinamide riboside Chloride foda na iya haɓaka haɓakar ƙwayar cuta, kariya daga ƙoshin abinci mai ƙarancin abinci mai haɗari. Nicotinamide riboside Chloride yana rage lalacewar hankali a cikin ƙirar linzamin ƙwayar cuta na cutar Alzheimer.

 

reference

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[8] Bing Gong, et al. Nicotinamide Riboside Ya Maida Ganewa Ta hanyar Tsara Ka'idojin Karɓar Mai Karɓar-γ Coactivator 1α An βara β-Sirrin 1 Rushewa da Bayyana Maɓallin Masarauta a Models Mouse. Neurobiol tsufa. 2013 Jun; 34 (6): 1581-8.

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