Samfur Description
Orlistat foda video- AASraw
Orlistat foda Asalin Halaye
| name: | Orlistat foda |
| CAS: | 96829-58-2 |
| Formula kwayoyin: | C29H53NO5 |
| Kwayoyin Weight: | 495.7 |
| Shawarwar Melt: | 50 ° C |
| Ajiye Temp: | 2-8 ° C |
| Color: | White foda |
Menene Orlistat Foda?
Orlistat foda wani magani ne da aka yi amfani da shi don maganin kiba ko marasa lafiya.Roche ne ya fara haɓaka shi kuma ya kaddamar da shi a Amurka a cikin 1999. Shi ne kawai maganin asarar nauyi a kan-da-counter wanda FDA, CFDA da kuma Ema Yana aiki ta hanyar hana pancreatic lipases na ciki, enzymes da ke da alhakin rushe kitse na abinci a cikin gastrointestinal tract.
A {asar Amirka, an amince da Orlistat don kula da ma'auni na jiki (BMI, Body Mass Index, Unit kg/㎡) ya kai ko wuce 30 (ma'aunin kiba na Amurka) da kuma, mutanen da ke da ma'auni tsakanin 27 da 30 da sauran matsalolin lafiya kamar hawan jini ko ciwon sukari.
Yaya Orlistat Foda ke Aiki?
Orlistat foda yana aiki ta hanyar hana lipases na ciki da pancreatic, wanda shine enzymes da ke da alhakin rushe triglycerides a cikin ƙananan acid acid wanda za'a iya tunawa da jiki. rage yawan kitsen abincin da ake sha.
Tun da triglycerides ba a rushe su cikin fatty acids kyauta, ana fitar da su ba tare da canzawa ba a cikin feces. Wannan tsari yana haifar da raguwa a cikin abincin caloric kuma yana inganta asarar nauyi. An nuna Orlistat don hana kusan 30% na kitsen abinci daga sha.
Bugu da ƙari, hana lipases, orlistat kuma yana hana yankin thioesterase na fatty acid synthase (FAS) .Wannan enzyme yana da hannu a cikin yaduwar kwayoyin cutar kansa amma ba kwayoyin halitta ba. -manufa ko rashin lafiyar bioavailability, na iya kawo cikas ga aikace-aikacen sa azaman ingantacciyar wakili na antitumor.
Gabaɗaya, tsarin aikin Orlistat ya ƙunshi hana enzymes da ke cikin narkewar mai, wanda ke haifar da raguwar adadin kitse na abinci mai narkewa da haɓaka asarar nauyi.
Fa'idodin Amfani da Orlistat Foda
Orlistat foda magani ne da aka fi amfani dashi don magance kiba, da farko ta hanyar hana shan mai daga abincin ɗan adam. Bugu da ƙari, yana iya rage yawan hawan jini kuma yana bayyana don hana farawar nau'in ciwon sukari na 2, ko daga asarar nauyi kanta ko wasu. tasiri.
· Jiyya na Kiba
Ana amfani da Orlistat foda da farko don maganin kiba a cikin haɗin gwiwa tare da mai bada sabis na kiwon lafiya-mai kulawa da rage yawan adadin kuzari.Aikinsa na farko shine don hana shayar da kitsen abinci ta hanyar yin aiki a matsayin mai hana lipase, don haka rage yawan caloric.AASraw Orlistat foda yana aiki. Ta hanyar hana lipase na ciki da pancreatic lipase, enzymes da ke da alhakin rushe triglycerides a cikin hanji. Lokacin da aka katange ayyukan lipase, triglycerides daga cikin abincin ba a sanya su cikin acid fatty free absorbable, maimakon haka an cire su ba canzawa.
Bayanan da aka tattara daga gwaje-gwaje na asibiti sun nuna cewa mutanen da aka ba wa orlistat ban da gyare-gyaren salon rayuwa, irin su abinci da motsa jiki, sun rasa kimanin kilogiram 2-3 (4-7 lb) fiye da wadanda ba sa shan miyagun ƙwayoyi a tsawon shekara guda. Tsakanin 35.5 % da 54.8% na batutuwa sun sami raguwar 5% ko mafi girma a cikin tarin jiki, ko da yake ba duk wannan taro ba dole ne ya kasance mai kiba. Tsakanin 16.4% da 24.8% sun sami raguwa aƙalla 10% na kitsen jiki. Yana da kyau a lura cewa bayan haka. An dakatar da orlistat, adadi mai mahimmanci na batutuwa sun dawo da nauyi-har zuwa 35% na nauyin da suka rasa.
· Rage Hawan Jini
Baya ga taimakawa wajen asarar nauyi, binciken ya nuna cewa orlistat foda zai iya haifar da raguwa mai sauƙi a cikin karfin jini. Bayanan da aka tattara daga gwaje-gwaje na asibiti sun nuna cewa orlistat yana rage karfin jini na systolic da diastolic ta matsakaicin 2.5 da 1.9 mmHg, bi da bi. Ana tunanin hanyar da ke bayan wannan raguwar hawan jini yana da alaƙa da asarar nauyi da aka samu ta hanyar amfani da orlistat, kamar yadda kiba sanannen abu ne mai haɗari ga hauhawar jini. Duk da haka, yana da mahimmanci a lura cewa rage yawan hawan jini da aka samu ta hanyar amfani da orlistat. ƙananan ƙananan kuma bai kamata a dogara da shi azaman maganin hawan jini kawai ba. Mutanen da ke fama da hawan jini ya kamata su ci gaba da bin shawarar mai kula da lafiyar su kuma su yi amfani da magani kamar yadda aka tsara.
· Rigakafin Faruwar Ciwon Ciwon Nau'i Na Biyu
Orlistat foda an nuna cewa yana da tasiri mai kariya akan farkon nau'in ciwon sukari na 2, ban da asarar nauyi da rage yawan karfin jini. Wannan yana iya yiwuwa saboda gaskiyar cewa kiba shine babban haɗari don bunkasa ciwon sukari na 2, kuma Orlistat na iya taimakawa tare da asarar nauyi a cikin mutane masu kiba.Bincike ya nuna cewa orlistat na iya rage yawan ciwon sukari na 2 a cikin mutanen da ke da kiba a kusa da adadin da canjin salon rayuwa ke yi.Hanyar hanyar da orlistat ke hana farawar ciwon sukari na 2. ba a fahimta sosai ba, amma ana tunanin yana da alaƙa da ikon da miyagun ƙwayoyi ke da shi don rage yawan adadin kuzari ta hanyar hana ɗaukar kitse na abinci, wanda zai iya haifar da haɓakar haɓakar glucose da haɓakar insulin. don ingantaccen salon rayuwa, kuma amfani da shi ya kamata koyaushe a haɗa shi tare da rage yawan adadin kuzari da motsa jiki don matsakaicin tasiri.
Bayanan kula: Don haɓaka fa'idodin Orlistat foda, yana da mahimmanci don siyan shi daga amintaccen mai ba da sabis.AASraw yana ba da babban ingancin Orlistat foda a farashin da ya dace, a matsayin ƙwararrun Orlistat foda mai kaya tare da cibiyar R & D mai zaman kanta da ma'aikata.Lokacin da ka sayi Orlistat foda. daga AASraw, za ku iya kasancewa da tabbaci cewa kuna samun samfur mai tsabta, mai inganci wanda ya dace da buƙatun ingancin inganci.
Halayen Tasirin Orlistat Foda?
Orlistat foda, kamar kowane magani, yana da tasiri mai tasiri.Ko da yake kawai yana rinjayar tsarin gastrointestinal kuma ba tsarin zuciya da jijiyoyin jini ko na tsakiya ba, ba za a iya watsi da illa ba.
Abubuwan sakamako na al'ada
Tafarnuwa mai mai ko tabo mai tabo
- flatulence
- Ciwan ciki
- Gaggawar stool
- Ƙara mitar stool
- Fashin incontinence
- Mutuwar ta
- Ƙara yawan flatus na ciki
- Fatty (mai) stools
- Steatorrhea
Yayin da mai abun ciki a cikin abincin ya karu, yawan abin da ya faru kuma yana ƙaruwa daidai. Yawancin marasa lafiya na iya ingantawa bayan shan magani na wani lokaci.
Mummunan halayen ciki
- Ciwon ciki/rashin jin daɗi
- Ruwan ruwa
- Soft stools
- Ciwon dubura/rashin jin daɗi,
- Rashin jin daɗi
- Gum rashin jin daɗi
Bayanan kula: Yana da mahimmanci a lura cewa ingancin orlistat foda yana da alaƙa da alaƙa da sakamako masu illa, kuma ingancin foda mai inganci na iya rage haɗarin illa. yadda ya kamata.AASraw yana ba da babban ingancin Orlistat foda da aka ƙera a ƙarƙashin ƙayyadaddun ƙayyadaddun GMP masu tabbatar da tsabta da ƙarfi.Duk da haka, yana da mahimmanci don tuntuɓar ƙwararrun ma'aikatan kiwon lafiya koyaushe kafin fara wani sabon magani ko ƙarin tsarin.
Sashi da Gudanarwa na Orlistat foda don Magana
Orlistat foda shine magani na likitancin da aka yi amfani da shi don kula da asarar nauyi da kuma kula da nauyi lokacin da aka yi amfani da shi tare da rage yawan adadin kuzari.Shawarar da aka ba da shawarar da kuma gudanar da Orlistat foda sune kamar haka.
sashi
Shawarar da aka ba da shawarar Orlistat foda shine 120 MG da aka yi ta baki sau 3 a rana tare da kowane abinci mai mahimmanci wanda ya ƙunshi mai. Jimlar adadin yau da kullum bai kamata ya wuce 360 MG ba.
Administration
Orlistat foda ya kamata a dauki baki a lokacin, ko har zuwa sa'a daya bayan, kowane abinci mai mahimmanci wanda ya ƙunshi mai. Idan an rasa abinci ko ba shi da mai, za a iya tsallake kashi na Orlistat foda.Ya kamata a shawarci marasa lafiya su dauki multivitamin dauke bitamin mai-mai narkewa aƙalla sa'o'i biyu kafin ko bayan shan Orlistat foda.
Daidaita sashi
Babu wani daidaita kashi da ake bukata ga marasa lafiya da ke da ciwon koda ko hanta. Duk da haka, marasa lafiya da ciwon sukari na iya buƙatar daidaita kashi na magungunan ciwon sukari, kuma ya kamata a kula da sarrafa glycemic a hankali.
Tsanani
Yana da mahimmanci a lura cewa Orlistat foda bai kamata a yi amfani da shi ba a lokacin daukar ciki ko kuma wadanda ke da ciwon malabsorption na yau da kullum, cholestasis, ko hypersensitivity ga abu mai aiki ko duk wani kayan haɓaka samfurin. a hankali.
Notes
Bayanin sashi da bayanin gudanarwa da aka bayar game da Orlistat foda shine don dalilai na bayanai kawai kuma bai kamata a yi amfani da shi azaman madadin shawarwarin likita na sana'a ba.Koyaushe tuntuɓi mai bada sabis na kiwon lafiya kafin fara wani magani ko kari, ciki har da Orlistat foda.Da sashi da gudanarwa na Orlistat. foda ya kamata a ƙayyade bisa ga tarihin likita na mutum, magunguna na yanzu, da sauran abubuwan da suka dace. Bugu da ƙari, sayen orlistat foda tare da babban inganci daga abin dogara Orlistat foda mai kaya ko mai sayarwa yana da mahimmanci.
Ayyukan Orlistat tare da Wasu Magunguna
- Orlistat zai iya rage sha na bitamin A, D da E. Don haka, idan kuna shan shirye-shiryen da ke dauke da bitamin A, D da E (kamar wasu shirye-shiryen multivitamin), ya kamata ku ɗauki bitamin 2 hours bayan shan orlistat.
- Marasa lafiya da ke da nau'in ciwon sukari na 2 na iya buƙatar rage adadin magungunan hypoglycemic na baka (kamar sulfonylureas).
- Gudanar da haɗin gwiwar orlistat tare da cyclosporine na iya haifar da raguwa a cikin ƙwayar plasma na ƙarshen.
- Lokacin amfani da orlistat a hade tare da amiodarone, yana iya rage sha na ƙarshen kuma ya rage tasirin warkewa.
- Idan ana amfani da shi tare da wasu magunguna a lokaci guda, hulɗar magunguna na iya faruwa, da fatan za a tuntuɓi likitan ku ko likitan magunguna don cikakkun bayanai.
Inda zan saya Orlistat Foda?
Nemo abin dogara kuma mai daraja Orlistat foda mai kaya yana da mahimmanci ga waɗanda ke cikin masana'antar magunguna ko masana'antar kiwon lafiya waɗanda ke buƙatar wannan magani don samfuran su ko marasa lafiya. .Mai mai ba da kaya ya kamata ya kasance yana da kyakkyawar rikodi game da kula da inganci, marufi, jigilar kaya, da sabis na abokin ciniki.Ta hanyar zaɓar mai siyar da abin dogara, abokan ciniki na iya tabbatar da cewa sun sami samfurin aminci da inganci don bukatun su.
AASraw shi ne mai samar da kayan aiki mai mahimmanci na kayan aikin magunguna, ciki har da Orlistat foda. Suna da tsarin kulawa mai mahimmanci don tabbatar da cewa samfurorin su suna da inganci kuma sun dace da ka'idodin da ake bukata. batch na Orlistat foda suna sayar da su, don haka za a iya tabbatar da ku da tsabta da ingancin samfurin. Bugu da ƙari, AASraw yana ba da farashi mai mahimmanci da kuma isar da abin dogara, waɗanda suke da muhimman abubuwan da za a yi la'akari da lokacin zabar mai sayarwa.Gaba ɗaya, AASraw shine mai sayarwa mai daraja. na Orlistat foda wanda ke ba da samfurori masu inganci, farashin gasa, da isar da abin dogara.
Orlistat foda Rahoton Gwaji-HNMR
Menene HNMR kuma Menene Bakan HNMR ke gaya muku?H Nuclear Magnetic Resonance (NMR) spectroscopy dabara ce ta nazarin sinadarai da ake amfani da ita wajen sarrafa inganci da bincike don tantance abun ciki da tsarkin samfurin da kuma tsarinsa na kwayoyin halitta. Misali, NMR na iya tantance gaurayawan da ke dauke da sanannun mahadi. Don mahaɗan da ba a san su ba, NMR ana iya amfani da su ko dai don daidaitawa da ɗakunan karatu na bakan gizo ko don fahimtar ainihin tsarin kai tsaye. Da zarar an san ainihin tsarin, ana iya amfani da NMR don ƙayyade daidaituwar kwayoyin halitta a cikin bayani tare da nazarin kaddarorin jiki a matakin kwayoyin halitta kamar musanya mai daidaituwa, canje-canjen lokaci, solubility, da yadawa.
Orlistat foda (96829-58-2) -COA
Orlistat foda (96829-58-2) -COA
Yadda za a saya Orlistat Foda daga AASraw?
❶Don tuntuɓar mu ta tsarin binciken imel ɗin mu, ko kuma ku bar mana lambar ku ta whatsapp, wakilin sabis na abokin ciniki (CSR) zai tuntuɓar ku cikin awanni 12.
❷Don samar mana da adadin ku da adireshin ku.
❸CSR ɗin mu zai ba ku fa'ida, lokacin biyan kuɗi, lambar bin diddigi, hanyoyin bayarwa da ƙididdigar ranar isowa (ETA).
❹An gama biyan kuɗi kuma za a aika da kayan a cikin awanni 12.
❺Kayan da aka karɓa kuma a ba da sharhi.
Marubucin wannan labarin:
Dr. Monique Hong ya sauke karatu daga Kwalejin Kimiyya ta Burtaniya ta London Faculty of Medicine
Mawallafin Jaridar Kimiyya:
1. CC Carson
Sashen tiyata, Sashen Urology, Jami'ar North Carolina, Chapel Hill, NC,
2. I. Eardley
Asibitin Jami'ar St. James, Leeds, UK,
3. DJ Walker
Eli Lilly and Company, Indianapolis, IN, Amurka
4. WH Cordell
Eli Lilly and Company, Indianapolis, IN, Amurka
Babu wata hanya da wannan likita/masanin kimiyyar ya yarda ko ba da shawarar siyan, siyarwa, ko amfani da wannan samfur saboda kowane dalili. Aasraw ba shi da wata alaƙa ko alaƙa, a fayyace ko akasin haka, tare da wannan likitan. Manufar ambaton wannan likita shine yarda, yarda da kuma yaba da cikakken bincike da ayyukan ci gaba da masana kimiyyar da ke aiki akan wannan abu suka yi.
References
[1] Siebenhofer A,Winterholer S,Jeitler K,Horvath K,Berghold A,Krenn C,Semlitsch T (Janairu 2021). "Tsarin dogon lokaci na magungunan rage nauyi a cikin mutanen da ke da hauhawar jini". Rukunin Bayanai na Cochrane na Sharhin Tsare-tsare. 1 (1): CD007654.
[2] Mancini MC,Halpern A (Afrilu 2006). "Pharmacological lura da kiba". Arquivos Brasileiros de Endocrinologia da Metabologia. 50 (2): 377-389.
[3] Heck AM, Yanovski JA, Calis KA (Maris 2000). "Orlistat, sabon mai hana lipase don sarrafa kiba". Pharmacotherapy. 20 (3): 270-279.
[4] Garcia SB, Barros LT, Turatti A, Martinello F, Modiano P, Ribeiro-Silva A, et al. (Agusta 2006) "Aikin anti-kiba Orlistat yana da alaƙa da haɓaka alamun preneoplastic na colonic a cikin berayen da aka bi da su tare da sinadarin carcinogen. ". Wasiƙun Ciwon daji. 240 (2):221–224.
[5] "FDA Ta Amince da Orlistat don Amfani da Kan-Aiki" (Sakawar Latsa).USFood and Drug Administration (FDA).7 Fabrairu 2007.Tare daga ainihin a ranar 13 ga Mayu 2009. An dawo da 7 Fabrairu 2007.
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