Samfur Description
Menene PT-141 (Bremelanotide)?
PT-141, kuma aka sani da bremelanotide,sunan jinsi ne na sabon nau'in peptides wanda ake nazarin don taimakawa wajen inganta aikin jima'i (rashin karfin jima'i, ko rashin ƙarfi) a cikin maza da kuma taimakawa wajen inganta jima'i (cututtukan jima'i) a cikin mata.141 baya aiki akan tsarin jijiyoyin jini. kamar sauran mahadi guda biyu da suka gabata, amma an san shi kuma an nuna shi don taimakawa wajen ƙara yawan jima'i a cikin maza da mata masu shayarwa.Bugu da ƙari, peptide PT 141 yanzu FDA-an yarda don magance matsalar jima'i a cikin mata.Idan mutane suna so su sayi peptide PT. 141 akan layi, kafofin da yawa, kamar PT 141 masana'anta da mai siyarwa, ana iya samun sauƙin samu.
Ta yaya PT-141 (Bremelanotide) ke aiki?
PT-141 (Bremelanotide) shine na farko na madadin nau'in magungunan da aka sani da melanocortin agonists don maganin cututtuka.Hanyar aikin PT-141 (Bremelanotide) na iya samar da mahimman aminci da fa'idodin inganci idan aka kwatanta da samfuran da ake samu a halin yanzu saboda yana aiki akan. Hanyoyi na sarrafawa ayyuka maimakon kai tsaye a kan tsarin.Clinical bayanai sun nuna cewa PT-141 (Bremelanotide) kuma iya yadda ya kamata bi daban-daban impotence marasa lafiya.The hanci tsari na PT-141 (Bremelanotide) a karkashin ci gaba ne kamar yadda dace a matsayin baka far, yana da kyau sosai. mai haƙuri idan aka kwatanta da jiyya masu ɓarna kamar allura da pellets transurethral, kuma ya bayyana yana da saurin farawa.
Bremelanotide PT-141 an ce yana aiki ta hanyar kunna masu karɓa na melanocortin a cikin kwakwalwa, don haka yana taimakawa wajen ƙara yawan sha'awar jima'i. Yana da peptide na tushen melanocortin wanda ya nuna tasiri a cikin nazarin asibiti a cikin ratsan namiji da mace. a matsayin ƙasa kamar 1-2 MG, yayin da yawancin berayen mata sun nuna amsa mai kyau a cikin allurai kamar 2-3 MG. Dosage bukatun sun kasance mafi girma ga berayen mata, amma an sami sakamako mai ƙarfi a cikin berayen mata.
Yana da mahimmanci a lura cewa tsarin aikin samfurin yana da alaƙa da ingancinsa.Saboda masu inganci kawai na iya samun ingantacciyar hanyar aiki.Don tabbatar da ingancin PT-141, yana da mahimmanci don samun shi daga abin dogaro. source.AASraw, mai sana'a mai daraja da mai ba da kaya na PT-141, yana ba da samfurori masu kyau na peptide don bincike mai zaman kanta da cibiyoyin ci gaba da masana'antu.Idan kana da takamaiman buƙatu, zabar PT-141 mai girma daga AASraw shine kyakkyawan zaɓi.
Amfanin amfani da peptide PT-141 (Bremelanotide)
PT-141 (Bremelanotide) yana ba da fa'idodi na farko wajen magance tabarbarewar jima'i a cikin maza da mata.Lokacin da aka gudanar ta hanyar allura, ya nuna sakamako mai ban sha'awa musamman a cikin abubuwan gwajin mata. low libido, da rashin ƙarfi.
Ƙara sha'awar jima'i
Ɗaya daga cikin mahimman fa'idodin PT-141 shine ikonsa na haɓaka sha'awar jima'i ta hanyar tsarin kulawa na tsakiya ba tare da mummunar tasiri ga tsarin jijiyoyin jini ba.Idan aka kwatanta da sauran magungunan jima'i na jima'i, AASraw PT-141 yana dauke da karfi yayin da yake ci gaba da kiyaye aminci mai kyau. profile.Ba ya haifar da babban haɗari ga lafiyar mutum gaba ɗaya.
A cikin maganin tabarbarewar jima'i, an nuna PT-141 yadda ya kamata don haɓaka sha'awar jima'i a cikin mata, kuma tasirin zai iya zama na dindindin. Wasu mutane suna samun fa'ida har zuwa sa'o'i 72 bayan allurar PT-141.
Ƙara makamashi
Baya ga rawar da yake takawa wajen magance tabarbarewar jima'i, PT-141 ya nuna yiwuwar haɓaka matakan makamashi ta hanyar halitta.Cibiyoyin hormone na maza kuma suna amfani da PT-141 don magance alamun da ke da alaƙa da ƙananan testosterone.The peptide blend of PT-141 iya zama da amfani ga mutane. wanda akai-akai yana fuskantar gajiya, gajiya, ko rashin kuzari.
Magance matsalar launin fata.
Bugu da ƙari kuma, an bincika PT-141 don yuwuwar sa wajen magance cututtukan cututtukan fata kuma an yi amfani da shi azaman na halitta, wakili na tanning ba tare da rana ba. Duk da haka, haɓakar PT-141 don haifar da sha'awar jima'i a cikin masu amfani ya iyakance aikace-aikacen sa a cikin samfuran tanning. Yana da mahimmanci a lura cewa ainihin dalilin amfani da PT-141 ya kasance maganin rashin aiki iri-iri da haɓaka sha'awar jima'i a cikin maza da mata.
Yana da mahimmanci don siyan PT-141 daga tushe masu daraja; in ba haka ba, ba za ku iya samun mafi kyawun inganci daga PT-141. A matsayin mai sana'a na PT-141 mai sana'a da mai sayarwa, AASraw yana nufin samar da PT-141 mai tsabta a dukan duniya. Idan kuna da buƙatu, AASraw's peptide PT-141 babban zabi ne a gare ku.
Abubuwan da ke haifar da peptide PT-141 (Bremelanotide)
Duk da yake PT-141 (Bremelanotide) yana da jurewa da kyau, yana da mahimmanci a san abubuwan da za su iya haifar da sakamako masu illa.
Tashin zuciyaTashin zuciya yana daya daga cikin abubuwan da aka fi sani da PT-141. Yana iya haifar da jin dadi ko tashin ciki.
ciwon kai: Wasu mutane na iya samun ciwon kai a matsayin sakamako mai tasiri na PT-141. Wadannan ciwon kai yawanci suna da sauƙi kuma suna warware kansu.
Allura shafin martani: Tun da PT-141 ana gudanar da shi ta hanyar allura, akwai yuwuwar fuskantar halayen wurin allura kamar zafi, ja, ko kumburi a wurin allurar.
Dizziness: Dizziness ko lightheartedness na iya faruwa a matsayin sakamako na PT-141. Yana da mahimmanci don kauce wa ayyukan da ke buƙatar faɗakarwa idan kun fuskanci dizziness.
gajiyaWasu mutane na iya samun gajiya ko gajiya bayan shan PT-141.
Maƙarar Nasal: Idan PT-141 ana gudanar da shi a cikin nau'in feshin hanci, cunkoson hanci ko cushewa na iya faruwa a matsayin sakamako mai illa.
Yana da mahimmanci a lura cewa ba kowa ba ne zai fuskanci waɗannan illolin, kuma tsanani da yawan tasirin sakamako na iya bambanta tsakanin daidaikun mutane. Idan kun fuskanci wani abin da ya shafi ko kuma na ci gaba da illa, ana ba da shawarar ku tuntuɓi mai sana'a na kiwon lafiya don ƙarin jagora. .Bugu da ƙari, lokacin siyan PT-141, kuna buƙatar zaɓar mai siyarwar PT-141 a hankali don tabbatar da ingancin samfurin.
PT-141 vs Melanotan II (MT-2)
PT-141 (Bremelanotide) da Melanotan II (MT-2) suna da wasu bambance-bambance a cikin tasirinsu da hanyoyin aiwatar da su yayin da ake magana da matsalar rashin karfin mazakuta (ED).Ga kwatance tsakanin PT-141 da MT-2 game da su. tasiri a kan ED.
① Tsarin Aiki
DA-141-B
PT-141 da farko yana aiki akan tsarin juyayi na tsakiya ta hanyar niyya masu karɓa na melanocortin, musamman melanocortin 4 receptor (MC4R) a cikin kwakwalwa. Yana ƙarfafa sakin nitric oxide, wanda ke taimakawa shakatawa masu santsi a cikin azzakari kuma yana haɓaka kwararar jini, yana haifar da inganta aikin mizani.
Melanotan II
Melanotan II yana aiki da farko ta hanyar ƙaddamar da masu karɓar melanocortin, musamman melanocortin 1 receptor (MC1R) .Manufarsa ta farko ita ce ta haɓaka samar da melanin a cikin fata, wanda ke haifar da duhun fata. Ayyukan erectile ba su da ƙasa kai tsaye idan aka kwatanta da PT-141.
②Mayar da hankali kan Rashin Maza
DA-141-B
PT-141 an yi nazari na musamman kuma an samar da shi don magance tabarbarewar jima'i, gami da tabarbarewar mazakuta, a tsakanin maza da mata. Gwajin asibiti ya nuna sakamako mai ban sha'awa na inganta aikin erectile da sha'awar jima'i.
Melanotan II
Duk da yake Melanotan II an ba da rahoton anecdotally don samun wasu tasiri akan aikin jima'i da libido, manufarsa ta farko ba ta mayar da hankali ga magance dysfunction erectile ba. Ana amfani da shi da farko don tasirin tanning kuma yana da ƙayyadaddun shaidar asibiti da ke tallafawa amfani da shi wajen magance ED.
③Shaidar asibiti
DA-141-B
PT-141 ya yi gwajin gwaji na asibiti musamman yana kimanta tasirinsa wajen magance matsalar rashin karfin mazakuta.Wadannan gwaje-gwajen sun nuna sakamako mai kyau, yana nuna yiwuwarsa azaman zaɓin magani ga ED.
Melanotan II
Melanotan II yana da ƙayyadaddun shaida na asibiti da ke goyan bayan tasirinsa wajen magance matsalar rashin karfin mazakuta.Mafi yawan bayanan da ake samu game da tasirin sa akan aikin jima'i yana dogara ne akan rahotannin anecdotal maimakon nazarin asibiti mai tsanani.
A taƙaice, PT-141 an yi nazari da yawa kuma an haɓaka shi don magance tabarbarewar erectile da tabarbarewar jima'i a cikin maza da mata.Tsarin aikin sa kai tsaye yana kaiwa ga tsarin juyayi na tsakiya kuma ya nuna sakamako mai ban sha'awa a cikin gwaji na asibiti.A daya bangaren kuma. hannu, Melanotan II da farko yana mai da hankali kan duhun fata kuma yana da ƙarancin shaidar kai tsaye don tasirin sa wajen magance matsalar rashin ƙarfi.
Inda zan sayi PT-141 (Bremelanotide)?
Lokacin da yazo ga PT-141 (Bremelanotide), yana da mahimmanci don ba da fifiko ga aminci da amincin lokacin yin la'akari da siyan siye daga masu samar da kan layi.Ya kamata a nemi maɓuɓɓuka masu inganci da aminci don tabbatar da inganci da ingancin samfurin don aikace-aikacen kiwon lafiya da aka yi niyya.Tabbaci Sunan mai kaya yana da mahimmanci, kamar yadda suke bin ka'idodin kula da inganci da kuma samar da takaddun da suka dace kamar Takaddun Bincike.
Idan kana neman tushen abin dogara don siyan PT-141, AASraw na iya zama zaɓi mai dacewa.AASraw kamfani ne wanda ke ba da nau'ikan peptides da yawa, gami da PT-141. Abubuwan samfuran su galibi ana amfani da su ta dakunan gwaje-gwaje da cibiyoyin bincike don haɓakawa da samar da samfuran lafiya daban-daban.
Rahoton Gwajin PT-141-HNMR
Menene HNMR kuma Menene Bakan HNMR ke gaya muku?H Nuclear Magnetic Resonance (NMR) spectroscopy dabara ce ta nazarin sinadarai da ake amfani da ita wajen sarrafa inganci da bincike don tantance abun ciki da tsarkin samfurin da kuma tsarinsa na kwayoyin halitta. Misali, NMR na iya tantance gaurayawan da ke dauke da sanannun mahadi. Don mahaɗan da ba a san su ba, NMR ana iya amfani da su ko dai don daidaitawa da ɗakunan karatu na bakan gizo ko don fahimtar ainihin tsarin kai tsaye. Da zarar an san ainihin tsarin, ana iya amfani da NMR don ƙayyade daidaituwar kwayoyin halitta a cikin bayani tare da nazarin kaddarorin jiki a matakin kwayoyin halitta kamar musanya mai daidaituwa, canje-canjen lokaci, solubility, da yadawa.
Yadda za a saya PT-141 daga AASraw?
❶Don tuntuɓar mu ta tsarin binciken imel ɗin mu, ko kuma ku bar mana lambar ku ta whatsapp, wakilin sabis na abokin ciniki (CSR) zai tuntuɓar ku cikin awanni 12.
❷Don samar mana da adadin ku da adireshin ku.
❸CSR ɗin mu zai ba ku fa'ida, lokacin biyan kuɗi, lambar bin diddigi, hanyoyin bayarwa da ƙididdigar ranar isowa (ETA).
❹An gama biyan kuɗi kuma za a fitar da kayan a cikin awanni 12.
❺Kayayyakin da aka karɓa kuma a ba da sharhi.
Marubucin wannan labarin:
Dr. Monique Hong ya sauke karatu daga Kwalejin Kimiyya ta Burtaniya ta London Faculty of Medicine
Mawallafin Jaridar Kimiyya:
1. Anita H. Clayton MD
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, Virginia
2. François Giuliano MD, PhD
Raymond Poincaré Hospital—Department of Physical Medicine and Rehabilitation, Garches, France
3. Mohammad Reza Safarinejad
Urology and Nephrology Research Center, Shaheed Modarress Hospital, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
4. Raymond C. Rosen PhD
Sashen Kula da Lafiyar Halitta, Jami'ar Medicine da Dentistry na New Jersey, Robert Wood Johnson Medical School, Piscataway, NJ, Amurka
Babu wata hanya da wannan likita/masanin kimiyyar ya yarda ko ba da shawarar siyan, siyarwa, ko amfani da wannan samfur saboda kowane dalili. Aasraw ba shi da wata alaƙa ko alaƙa, a fayyace ko akasin haka, tare da wannan likitan. Manufar ambaton wannan likita shine yarda, yarda da kuma yaba da cikakken bincike da ayyukan ci gaba da masana kimiyyar da ke aiki akan wannan abu suka yi.
References
[1].Simon JA,Kingsberg SA"Tsarin Tsawon Tsawon Lokaci da Ingantaccen Bremelanotide don Rashin Haɓaka Sha'awar Jima'i."Obstet Gynecol.2019 Nov.PMID:31599847.
[2] Diamond LE, Earle DC, Heiman JR, Rosen RC, Perelman MA, Harning R. J Jima'i Med.141 Jul; Saukewa: 2006.
[3] Ückert S,Bannowsky A,Albrecht K,Kuczyk MA (Nuwamba 2014) "Melanocortin agonists receptor agonists a cikin lura da maza da mata jima'i tabarbarewar: sakamakon daga asali bincike da kuma asibiti karatu ". 23):11–1477.doi:83/10.1517.PMID 13543784.2014.934805.
[4] Pfaus J, Giuliano F, Gelez H. "Bremelanotide: wani bayyani na ainihin tasirin CNS akan aikin jima'i na mata." J Jima'i Med.2007 Nov.PMID:17958619.
[5] Mintzes B, Tiefer L, Cosgrove L. "Bremelanotide da flibanserin don ƙananan sha'awar jima'i a cikin mata: kuskuren tsarin da aka tsara." Drug Ther Bull.2021 Dec; PMID: 34642243.
[6] Molinoff PB, Shadiack AM, Earle D, Diamond LE, Quon CY."PT-141: melanocortin agonist don maganin tabarbarewar jima'i"Ann NY Acad Sci.2003 Jun.PMID:12851303.
[7] Rosen RC, Diamond LE, Earle DC, Shadiack AM, Molinoff PB. "Kima da aminci, pharmacokinetics da pharmacodynamic sakamako na subcutaneously gudanar PT-141, melanocortin receptor agonist, a cikin lafiya maza batutuwa da kuma marasa lafiya tare da m. Amsa ga Viagra."Int J Impot Res.2004 Apr.PMID:14999221.
[8] Diamond LE, Earle DC, Garcia WD, Spana C." Gudanar da ƙananan allurai na intranasal PT-141, melanocortin agonist mai karɓa, da sildenafil ga maza masu fama da rashin ƙarfi suna haifar da ingantaccen amsawar mizani. "Urology. 2005 Afrilu; PMID: 15833522.
