Samfur Description
Menene TB-500?
TB500, wanda kuma aka sani da Thymosin Beta-4, shine peptide na roba wanda aka samo daga sunadaran da ke faruwa ta halitta mai suna thymosin beta-4. Ya ƙunshi jerin amino acid kuma ya kasance batun bincike da hasashe game da yiwuwar aikace-aikacen warkewa. .
Thymosin beta-4 ne ta halitta samar a cikin jikin mutum da kuma taka rawa a cikin daban-daban physiological matakai, ciki har da rauni waraka, gyara nama, da kuma tsari na kumburi.An samu a high yawa a cikin jini platelets, inda aka saki a mayar da martani ga rauni na nama.
TB500, sigar roba ta thymosin beta-4, ana amfani dashi sau da yawa a cikin saitunan gwaji kuma ya sami karbuwa a cikin al'ummomin wasan motsa jiki da gina jiki saboda ikon da ake iya faɗi don haɓaka farfadowa da haɓaka waraka. ƙara haɓakar tsoka, inganta sassauci, da rage kumburi.
TB 500 bayanan baya
Kamar yadda aka fada a baya, TB-500 wani nau'in roba ne na Thymosin Beta 4, peptide furotin da ke faruwa a zahiri a jikin dabbobi da mutane. Duk da cewa TB-500 yana samuwa don dalilai na bincike, yawancin likitocin dabbobi da ke gudanar da su suna amfani da shi. gwaje-gwajen asibiti ta amfani da TB-500 akan dawakai.
Binciken Thymosin a cikin dawakai ya fara ne a cikin shekarun 1960. Dr.Allan Goldstein ya kirkiro thymosin alpha 1 don haɓaka aikin ƙwayoyin rigakafi da thymosin beta 4 ko TB-500 don hanzarta warkarwa da gyaran rauni.
A farkon shekarun 2010, an yi jita-jita cewa za a yi amfani da nau'in roba na TB-500 sosai a cikin tseren dawakai. fafatawa da sauran dawakai.lt a wannan lokacin ne aka fara samar da matakan gano TB-500 a cikin dawakan tsere da gaske.
TB-500, Thymosin beta-4, da duk sauran abubuwan da aka samo daga wurin yanzu an hana su shiga gasar tseren dawaki, da kuma duk wasannin motsa jiki da ke ƙarƙashin Code of the World Anti-Doping Agency (WADA).
An fara amfani da Thymosin a kan mutane a cikin 1974, lokacin da yarinya mai ƙananan ƙwayar thymus ba ta aiki ba ta sami alluran abu. ,da gaggawar warkewa.
Ta yaya TB-500 (Thymosin Beta-4) ke aiki?
Ba a fahimci ainihin tsarin aikin TB500 (Thymosin Beta-4) ba, kuma ana ci gaba da gudanar da bincike don tabbatar da ainihin tasirin sa akan jiki.
Haɓaka ƙauran tantanin halitta
Ana tunanin TB500 don inganta ƙaurawar tantanin halitta, wanda shine tsarin da sel ke yin ƙaura zuwa wurin da aka samu rauni ko lalacewa. Zai iya taimakawa wajen jawo hankalin kwayoyin da ke da hannu wajen gyara nama da farfadowa zuwa wurin da ke fama da wahala, irin su ƙwayoyin cuta, fibroblasts, da sel endothelial. ,samun waraka da farfadowar nama.
Modulation na kumburi
Ta hanyar daidaitawa da tsarawa da aiki na ƙwayoyin ƙwayoyin ƙwayoyin cuta, TB500 na iya samun sakamako masu illa. yanayi mai kyau don warkarwa da gyaran nama ta hanyar rage kumburi.
Ƙarfafawar angiogenesis
Angiogenesis shine samuwar sabbin hanyoyin jini. An nuna TB500 don haɓaka angiogenesis, mai yuwuwa ta hanyar haɓaka haɓakar ƙwayoyin endothelial da ƙaura, wanda ke da mahimmanci ga halittar jini. don farfadowar nama.
Samar da collagen
Collagen wani furotin ne wanda ke ba da tallafi na tsarin kyallen takarda. An ba da shawarar TB500 don ƙara haɓakar collagen, wanda zai iya taimakawa wajen sake farfadowa da rauni.
TB-500 amfanin
TB-500 wani nau'in nau'in nau'in peptide ne na halitta wanda ke faruwa a cikin jikin ɗan adam.Ya sami farin jini a cikin al'ummomin wasan motsa jiki da gina jiki don amfanin sa. wasu fa'idodi masu yuwuwa waɗanda aka ba da shawarar:
Gyaran nama da farfadowa
An ba da shawarar TB-500 don tayar da gyare-gyaren nama da farfadowa. Zai iya inganta ci gaban sabbin hanyoyin jini (angiogenesis) kuma yana ƙarfafa samuwar sababbin nama, ciki har da tsokoki, tendons, ligaments, da fata. murmurewa daga raunin da ya faru, saboda yana iya hanzarta aikin warkarwa da inganta lafiyar nama gaba ɗaya.
An hanzarta warkar da raunuka
TB-500 na iya taimakawa wajen hanzarta warkar da raunuka daban-daban, irin su ƙwayar tsoka, sprains, da hawaye na ligament. An bayar da rahoton don rage lokacin dawowa da ake bukata bayan rauni ta hanyar inganta ƙaurawar salula da kuma yaduwa a wurin rauni. Wannan na iya haifar da saurin warkarwa da saurin dawowa zuwa aikin jiki.
Rage Kumburi
TB-500 yana nuna abubuwan anti-mai kumburi, wanda zai iya taimakawa rage kumburi a cikin jiki.Ya iya hana samar da ƙwayoyin cuta masu kumburi da haɓaka sakin abubuwan da ke hana kumburi, don haka rage kumburi da haɗin gwiwa. mutanen da ke da yanayin kumburi na yau da kullun kamar arthritis, tendonitis, ko bursitis.
Lafiyar haɗin gwiwa da haɗin gwiwa
Ta hanyar goyan bayan gyaran nama da rage kumburi, TB-500 na iya taimakawa wajen inganta haɗin gwiwa da lafiyar jiki. Zai iya inganta mutunci da elasticity na tendons, ligaments, da guringuntsi, yana haifar da ingantaccen aikin haɗin gwiwa, ƙara yawan sassauci, da rage haɗarin raunin da ya faru.
Inganta haɓakar tsoka da farfadowa
Duk da yake TB-500 kanta ba wani fili mai gina jiki kai tsaye ba, yana iya ba da gudummawa a kaikaice ga ci gaban tsoka da farfadowa.Ta hanyar inganta gyaran nama da rage kumburi, zai iya tallafawa tsarin dawowa bayan motsa jiki mai tsanani ko rauni.Wannan zai iya haifar da tsoka mai sauri. gyare-gyare da haɓaka, inganta ƙarfin tsoka, da rage ciwon tsoka.
Inganta ci gaban gashi
Akwai wasu shaidun anecdotal da ke nuna cewa TB-500 na iya samun sakamako mai kyau akan ci gaban gashi.An yi imani da haɓaka haɓakar jini da isar da abinci mai gina jiki zuwa ga gashin gashi, mai yuwuwa haɓaka gashi da kauri.Duk da haka, ana buƙatar ƙarin bincike don kafa wannan fa'ida. a qarshe.
Lafiya na jijiyoyin jini
An yi nazarin TB-500 don amfanin da zai iya amfani da shi a cikin lafiyar zuciya da jijiyoyin jini.Yana iya inganta ci gaban sabbin hanyoyin jini, inganta kwararar jini, da haɓaka aikin zuciya.Wadannan tasirin na iya zama da amfani ga mutanen da ke da cututtukan zuciya, irin su cututtukan zuciya ko na gefe. cutar jijiya.
Abin da Akwai nau'ikan TB-500?
Peptide raw foda tsari
TB500 raw foda shine albarkatun kasa don samar da lyophilized foda TB500 a cikin vial.Ba a shirye don amfani da mutane ba. Kawai don bincike.
Sake tsarin mulki
TB-500 (Thymosin Beta-4) yana samuwa a cikin nau'i na lyophilized foda don sake gyarawa.Wannan lyophilized foda yana yawanci ana ba da shi a cikin vials ko vial kits. ruwa, don ƙirƙirar maganin allura.
Yana da mahimmanci a lura cewa TB-500 peptide ce ta roba, kuma ba a samun ta ta wasu nau'ikan kamar allunan baka ko creams. Hanyar farko na gudanarwa shine ta hanyar allura, ko dai ta cikin muscular, ta cikin jijiyoyi, ko kuma ta subcutaneously, kamar yadda kiwon lafiya ya ƙaddara. sana'a.
Lokacin siyan TB-500, yana da mahimmanci don tabbatar da cewa kuna samo shi daga mai siye mai inganci kuma abin dogaro don tabbatar da inganci da amincin samfurin.AASRAW shine abin dogaro peptide masana'anta don amincewa.Domin oda peptide wholesale, za ku sami gasa sosai. farashin.
Peptide TB-500 jagorar yin amfani da sake gyarawa
TB 500
Idan aka yi la'akari da ƙarancin binciken da aka buga har zuwa yau akan TB-500, babu wani takamaiman shawarwarin sashi don dalilai na bincike.
Duk da haka, a cikin binciken kimiyya da na asibiti har zuwa yau, mafi yawan adadin adadin da aka ruwaito na TB-500 ya kasance 2-5 mg. TB-500 ana gudanar da shi ta hanyar subcutaneous (a karkashin fata) ko injections na ciki, ana gudanarwa sau biyu a mako, don tsawon makonni 4 zuwa 8, ya danganta da yanayin binciken. Wasu likitocin sun fi son ƙarin farawa mafi girma don makonni 1 zuwa 2 na farko, wanda ke biye da adadin kulawa daidai da rabin kashi na asali na makonni 2 zuwa 6 bayan haka.
Yadda ake amfani da TB-500?
Da farko, shirya maganin TB-500 ta hanyar haɗa nau'in foda na lyophilized tare da ruwa na bacteriostatic ko ruwa mara kyau. Da zarar an gauraya, zana ƙarar da ya dace kuma a yi shi cikin wurin da ake so bayan tsaftace wurin allurar tare da barasa.
Mutane da yawa sun fi son hanyar intramuscular ta hanyar shigar da allura kusa da wurin da aka ji rauni, yayin da hanyar jijiya ta ƙunshi gano madaidaicin jijiya don yin allura.
Bayan allura, a hankali tausa yankin na iya inganta ingantaccen rarraba peptide. Yana da mahimmanci a tuntuɓi ƙwararren masani na kiwon lafiya don jagorar keɓancewa da tabbatar da aminci da dacewa da amfani da TB-500.
Bugu da kari, dacewar adanawa da sarrafa peptide na da mahimmanci don kiyaye tasirin sa.
Sashi da bayanin gudanarwa da aka bayar anan don dalilai ne na bayanai kawai kuma bai kamata a yi la'akari da shi azaman shawarar likita ba. ƙwararren ƙwararren kiwon lafiya ne kawai zai iya ba da ingantacciyar jagorar keɓance dangane da keɓaɓɓen yanayin ku. Yana da mahimmanci don ba da fifiko ga lafiyar ku da amincin ku ta hanyar tuntuɓar ƙwararrun kiwon lafiya kafin amfani da kowane magani ko magani.
Wanene yakamata yayi amfani da TB-500?
Samar da TB500 yana da girma.Yana da sauƙin samun ɗaya saboda akwai TB500 da yawa don siyarwa akan layi.Ya kamata a ƙayyade amfani da TB-500 (Thymosin Beta-4) akan mutum ɗaya kuma ƙarƙashin jagorancin ƙwararrun kiwon lafiya. An fi amfani da shi a cikin mahallin masu zuwa:
'Yan wasa da masu sha'awar motsa jiki: TB-500 bincike peptide na iya amfani da 'yan wasa da kuma mutanen da ke da hannu a cikin ayyuka masu tsanani na jiki don tallafawa farfadowa na tsoka, inganta gyaran nama, da kuma yiwuwar haɓaka aikin. Zai iya taimakawa wajen farfadowa daga raunin da ya faru da kuma rage kumburi da ke hade da horo.
Rauni farfadowa: Duk wanda ke da rauni mai alaka da tsoka zai iya amfani da Tb-500.Peptide TB-500 sau da yawa ana amfani da shi ta mutanen da ke murmurewa daga raunin musculoskeletal, irin su ciwon tsoka, hawaye na ligament, ko tendonitis.Yana iya taimakawa wajen inganta warkarwa, farfadowar nama, da ragewa. kumburi a wuraren da suka ji rauni.
Yanayin Kumburi na yau da kullun: Mutanen da ke da cututtukan cututtuka na yau da kullum irin su arthritis, tendonitis, ko bursitis na iya yin la'akari da yin amfani da TB-500 a karkashin kulawar likita. An yi nazari don abubuwan da ke tattare da ƙwayoyin cuta da kuma yiwuwar rage alamun da ke hade da waɗannan yanayi.
Medicine Regenerative: Ana binciken TB-500 don aikace-aikacen da za a iya amfani da su a cikin maganin farfadowa. Zai iya samun amfani mai amfani a cikin raunin rauni, gyaran nama, da angiogenesis (ci gaban jini), yana sa ya dace a cikin yanayin kiwon lafiya daban-daban.
TB-500 aminci da illa
Ko da yake ba a yi cikakken nazarin TB-500 don kare lafiyar ɗan adam ba, bayanai na yanzu sun nuna cewa yana da lafiya kuma yana iya jurewa idan an gudanar da shi daidai. Abubuwan da ba su da kyau ba su da yawa, masu canzawa, da matsakaici. Waɗannan su ne wasu misalai:
- gajiya
- ciwon kai
- Tashin zuciya
- Dizziness
- Binciken Blurry
- Canje-canje a cikin bugun zuciya
- Kumburi a wurin allura
Duk da haka, saboda akwai ƙarancin bayanai game da amfani da ɗan gajeren lokaci ko na dogon lokaci a cikin batutuwan ɗan adam, an yi kira ga masu bincike da su yi taka tsantsan yayin gudanar da maganin TB-500. peptides na bincike gabaɗaya yana da wasu ƙananan ƙananan illa, kamar:
- Canje-canje a cikin hawan jini
- Canje-canje a ci
- Pain a kan shafin allura
Abubuwan da ba su da kyau yawanci suna raguwa da kansu kuma suna dacewa da yin amfani da ƙananan samfurori na peptide. Irin waɗannan samfurori, da aka saya daga masu ba da izini ba tare da izini ba, za a iya ɓata su ko kuma sun ƙunshi gurɓata masu cutarwa. Yayin da yawancin masana'antun peptide ke sayar da peptides, muna bada shawarar mai ba da AASRAW.
Matukar kuna yin komai daidai ta hanyar amfani da TB-500 (misali amfani da dabarun allura masu dacewa, adanawa da sake gyara peptide yadda yakamata, ƙididdige adadin daidai, samun TB-500 kawai na magunguna, da sauransu), yana da wuyar gaske zaku iya. gudanar da wadannan matsalolin.
Amma tabbas yana yiwuwa - ku tuna, rashin sakamako mai tsanani a cikin ƴan binciken asibiti da aka buga zuwa yau ba yana nufin ba za su wanzu ba ta atomatik lokacin da kuke amfani da TB-500.
Inda zan saya TB-500 akan layi?
Kuna iya samun masu samar da TB-500 da yawa akan layi.Wadannan gidajen yanar gizon za su iya siyar da peptides bisa doka kawai don dalilai na bincike.Don tabbatar da amincin TB-500, ana ba da shawarar cewa duk peptides za a siya daga masana'antun da suka cika ka'idodin aminci masu zuwa:
(1) Dole ne a keɓance peptides sosai don amfani a cikin saitunan bincike.
(2) Mai siyarwar bai kamata ya ba da garantin likita ko da'awar sakamakon gudanar da peptide ba.
(3) Dole ne samfuran peptide su zo tare da ingantattun takaddun shaida na bincike (CoAs).
Rahoton Gwajin TB-500-HNMR
Menene HNMR kuma Menene Bakan HNMR ke gaya muku?H Nuclear Magnetic Resonance (NMR) spectroscopy dabara ce ta nazarin sinadarai da ake amfani da ita wajen sarrafa inganci da bincike don tantance abun ciki da tsarkin samfurin da kuma tsarinsa na kwayoyin halitta. Misali, NMR na iya tantance gaurayawan da ke dauke da sanannun mahadi. Don mahaɗan da ba a san su ba, NMR ana iya amfani da su ko dai don daidaitawa da ɗakunan karatu na bakan gizo ko don fahimtar ainihin tsarin kai tsaye. Da zarar an san ainihin tsarin, ana iya amfani da NMR don ƙayyade daidaituwar kwayoyin halitta a cikin bayani tare da nazarin kaddarorin jiki a matakin kwayoyin halitta kamar musanya mai daidaituwa, canje-canjen lokaci, solubility, da yadawa.
Yadda za a saya TB-500 daga AASraw?
❶Don tuntuɓar mu ta tsarin binciken imel ɗin mu, ko kuma ku bar mana lambar ku ta whatsapp, wakilin sabis na abokin ciniki (CSR) zai tuntuɓar ku cikin awanni 12.
❷Don samar mana da adadin ku da adireshin ku.
❸CSR ɗin mu zai ba ku fa'ida, lokacin biyan kuɗi, lambar bin diddigi, hanyoyin bayarwa da ƙididdigar ranar isowa (ETA).
❹An gama biyan kuɗi kuma za a fitar da kayan a cikin awanni 12.
❺Kayayyakin da aka karɓa kuma a ba da sharhi.
Marubucin wannan labarin:
Dr. Monique Hong ya sauke karatu daga Kwalejin Kimiyya ta Burtaniya ta London Faculty of Medicine
Mawallafin Jaridar Kimiyya:
1. Ildiko Bock-Marquette
Department of Biochemistry and Medical Chemistry, University of Pecs, Medical School, Pecs H-7624, Hungary
2. Gabriel Sosne
Department of Ophthalmology, Visual & Anatomical Sciences, Kresge Eye Institute, Wayne State University School of Medicine,USA
3. Othman Othman
School of Life Sciences, Division of Physiology, Pharmacology & Neuroscience, University of Nottingham Medical School, Queens Medical Centre, United Kingdom
4. Harmanpreet Kaur
Department of Chemistry and Biochemistry, University of Windsor, Windsor, Ontario, Canada
Babu wata hanya da wannan likita/masanin kimiyyar ya yarda ko ba da shawarar siyan, siyarwa, ko amfani da wannan samfur saboda kowane dalili. Aasraw ba shi da wata alaƙa ko alaƙa, a fayyace ko akasin haka, tare da wannan likitan. Manufar ambaton wannan likita shine yarda, yarda da kuma yaba da cikakken bincike da ayyukan ci gaba da masana kimiyyar da ke aiki akan wannan abu suka yi.
References
[1] Ho EN, Kwok WH, Lau MY, Wong AS, Wan TS, Lam KK, Schiff PJ, Stewart, BD. Liquid chromatography-mass spectrometry.” J Chromatogr A. 500 Nov 2012;23:1265-57. doi: 69/j.chroma.10.1016. Epub 2012.09.043 Satumba 2012.PMID: 23
[2] Esposito S, Deventer K, Goeman J, Van der Eycken J, Van Eenoo P.” Haɗin kai da halayyar N-terminal acetylated 17-23 guntun thymosin beta 4 da aka gano a cikin TB-500, samfurin da ake zargin ya mallaki yuwuwar doping. ” Gwajin Kwaya. 2012 Satumba; 4 (9): 733-8. doi: 10.1002/dta.1402. Epub 2012 Satumba 7.PMID: 22962027
[3] Pipes GT, Yang J.” Kariyar Cardio ta Thymosin Beta 4.” Vitam Horm. 2016; 102: 209-26. doi: 10.1016/bs.vh.2016.04.004. Epub 2016 Mayu 31.PMID: 27450736
[4] Bock-Marquette I, Maar K. 4 Maris; 2023:116. doi: 109741/j.intimp.10.1016. Epub 2023.109741 Jan 2023.PMID: 27
[5] Belsky JB, Rivers EP, Filbin MR, Lee PJ, Morris DC." Thymosin beta 4 tsarin actin a cikin sepsis. 2018 Jul; 18 (sup1): 193-197. doi: 10.1080/14712598.2018.1448381. Epub 2018 Maris 6.PMID: 29508629
[6] Jing J, Tian T, Wang Y, Xu X, Shan Y. "Chromatogr A. 2022 Agusta 2; 1676: 463272. doi: 10.1016/j.chroma.2022.463272. Epub 2022 Yuni 22.PMID: 35802965
