Samfur Description
Menene Tirzepatide?
Tirzepatide magani ne na novel wanda aka yarda da FDA don kula da nau'in ciwon sukari na 2. Ba da ƙarancin asarar nauyi, sayan tirzepatide za a yi amfani da tambarin kashe kiba don maganin kiba.
Yana aiki azaman dual GLP-1 agonist da GIP agonist don haɓaka fa'idodi iri ɗaya waɗanda ake gani tare da magungunan GLP-1 kamar su. semaglutide.A halin yanzu ana aiwatar da shi azaman maganin ciwon sukari na layi na biyu, kama da magungunan GLP-1, kuma ana ba da shi azaman allurar subcutaneous sau ɗaya a mako. FDA ta amince da peptide Tirzepatide a watan Mayu 2022.
Ta yaya Tirzepatide ke aiki?
Tirzepatide shine peptide na roba; da polypeptide inhibitory dual gastric inhibitory (GIP) da glucagon-kamar peptide 1 (GLP-1) agonist mai karɓa. Ya ƙunshi amino acid 39 kuma analog ne na polypeptide na hana ciki. Yana haifar da raguwar hyperglycemia. Bugu da ƙari, Tirzepatide yana ƙara matakan adiponectin. Ƙarfinsa na ƙuna biyu yana haifar da raguwar hyperglycemia fiye da GLP-1 agonists kadai kuma yana rage yawan sha'awar mai amfani.
Amfanin Tirzepatide
Tirzepatide shine mai karɓar insulinotropic polypeptide (GIP) mai dogaro da glucose da kuma glucagon-kamar peptide-1 (GLP-1) agonist mai karɓa, wanda FDA ta amince da shi don magance nau'in ciwon sukari na 2. Yana da mahimmanci a lura cewa ba a yarda da tirzepatide ba. Yin maganin nau'in ciwon sukari na 1 na ciwon sukari kuma ba a yi nazari a cikin marasa lafiya tare da pancreatitis.Tirzepatide shine mai karɓar GIP da GLP-1 agonist mai karɓa, wanda ke haifar da ingantaccen ingantaccen sarrafa glycemic a cikin nau'in ciwon sukari na 2 da raguwa mai yawa.
Sakamakon Tirzepatide
Marasa lafiya masu kiba da nau'in ciwon sukari na 2 (T2D) ko masu kiba da T2D sun rasa kimanin kilo 34.4 (15.7%) na nauyin jiki tare da 10 MG da 15 MG na tirzepatide (Mounjaro; Eli Lilly da Kamfanin), bisa ga binciken daga SURMOUNT. -2 gwajin gwaji na duniya na 3. Musamman, tirzepatide a 10 MG ya rage nauyin jiki ta 5% ko fiye a cikin 79.2% na marasa lafiya da kuma rage yawan nauyin jiki ta 12.8%, yayin da kashi 15 na 82.7 ya rage nauyi a cikin 14.7% na marasa lafiya da kuma rage matsakaici. nauyin jiki da XNUMX%.
Tirzepatide Da Aka Yi Amfani Don Rage Nauyi
Tirzepatide, allura ce ta mako-mako sau ɗaya don rage sukarin jini.Tun daga 2022 ya nuna tasirin asarar nauyi mai ban mamaki, kuma yana kan ƙirar sauri-sauri don bita don kula da kiba.A matsakaici, marasa lafiya sun ga asarar nauyi mai ban mamaki. sama da kashi 20% na nauyin jikinsu na farko.
Tirzepatide da kuma Bayani na BPC157 yana taimakawa tare da asarar nauyi ta hanyar rage yawan abinci da rage saurin yadda abinci ke tafiya cikin sauri ta hanyar narkewar ku.Wannan na iya taimaka muku jin karin tsayi kuma rage yawan abincin da kuke ci.Bincike ya nuna wannan aikin na iya faruwa a cikin kwakwalwa.
Yadda yake aiki:
●Rage yawan cin abinci.
●Yana hana hanta yin da fitar da sukari da yawa.
●Yana rage saurin yadda abinci ke barin ciki.
●Jiki yana sakin insulin lokacin da sukarin jini yayi yawa.
●Jiki yana cire yawan sukari daga cikin jini.
Menene bambanci tsakanin Tirzepatide da Semaglutide?
Tirzepatide yana aiki akan BOTH GIP da GLP-1 masu karɓa, yayin da Semaglutide ke aiki kawai akan masu karɓar GLP-1. Dukansu kwayoyi suna da tasiri mai tasiri akan asarar nauyi. -kamar peptide-1) agonist mai karɓa. Dukansu suna cikin nau'in magungunan da aka sani da incretin mimetics amma suna da wasu bambance-bambance.
gyare-gyaren salon rayuwa da ƙuntatawa na calorie zai haifar da sakamako mafi kyau gaba ɗaya. Amfanin asarar nauyi yana inganta haɓakar cututtuka na kiba irin su ciwon sukari, hawan jini, ƙananan lipids na jini da cututtukan zuciya wanda za'a iya gani tare da kadan kamar 5% asarar nauyi.
Tirzepatide Side Effects
Abubuwan da aka fi sani da Tirzepatide sun hada da tashin zuciya, zawo, rage cin abinci, amai, maƙarƙashiya, rashin narkewar abinci, da ciwon ciki (ciki) ba.Waɗannan ba duka illolin Tirzepatide ba ne. Yi magana da mai kula da lafiyar ku game da duk wani illar da za ku iya. kwarewa.
Inda zan sayi Tirzepatide?
AASraw shine wuri mafi kyau don siyan Tirzepatide wholesale.Duk samfuranmu sun zo tare da takaddun shaida mai zaman kansa, wanda aka ba da takaddun shaida na ɓangare na uku don ganowa, tsabta, da maida hankali. Kuma muna da babban Tirzepatide don siyarwa a hannun jari!
AASraw ne Tirzepatide maroki da Tirzepatide manufacturer wanda ke da Lab mai zaman kanta da kuma babban ma'aikata a matsayin goyon baya, duk abin da za a yi za a yi a karkashin tsarin CGMP da tsarin kula da ingancin trackable. don siyan Tirzepatide akan layi, barka da zuwa ziyarci gidan yanar gizon mu(aasraw.com).
Rahoton Gwajin Tirzepatide-HNMR
Menene HNMR kuma Menene Bakan HNMR ke gaya muku?H Nuclear Magnetic Resonance (NMR) spectroscopy dabara ce ta nazarin sinadarai da ake amfani da ita wajen sarrafa inganci da bincike don tantance abun ciki da tsarkin samfurin da kuma tsarinsa na kwayoyin halitta. Misali, NMR na iya tantance gaurayawan da ke dauke da sanannun mahadi. Don mahaɗan da ba a san su ba, NMR ana iya amfani da su ko dai don daidaitawa da ɗakunan karatu na bakan gizo ko don fahimtar ainihin tsarin kai tsaye. Da zarar an san ainihin tsarin, ana iya amfani da NMR don ƙayyade daidaituwar kwayoyin halitta a cikin bayani tare da nazarin kaddarorin jiki a matakin kwayoyin halitta kamar musanya mai daidaituwa, canje-canjen lokaci, solubility, da yadawa.
Yadda ake siyan Tirzepatide daga AASraw?
❶Don tuntuɓar mu ta tsarin binciken imel ɗin mu, ko kuma ku bar mana lambar ku ta whatsapp, wakilin sabis na abokin ciniki (CSR) zai tuntuɓar ku cikin awanni 12.
❷Don samar mana da adadin ku da adireshin ku.
❸CSR ɗin mu zai ba ku fa'ida, lokacin biyan kuɗi, lambar bin diddigi, hanyoyin bayarwa da ƙididdigar ranar isowa (ETA).
❹An gama biyan kuɗi kuma za a fitar da kayan a cikin awanni 12.
❺Kayayyakin da aka karɓa kuma a ba da sharhi.
Marubucin wannan labarin:
Dr. Monique Hong ya sauke karatu daga Kwalejin Kimiyya ta Burtaniya ta London Faculty of Medicine
Mawallafin Jaridar Kimiyya:
1. CC Carson
Sashen tiyata, Sashen Urology, Jami'ar North Carolina, Chapel Hill, NC,
2. I. Eardley
Asibitin Jami'ar St. James, Leeds, UK,
3. DJ Walker
Eli Lilly and Company, Indianapolis, IN, Amurka
4. WH Cordell
Eli Lilly and Company, Indianapolis, IN, Amurka
Babu wata hanya da wannan likita/masanin kimiyyar ya yarda ko ba da shawarar siyan, siyarwa, ko amfani da wannan samfur saboda kowane dalili. Aasraw ba shi da wata alaƙa ko alaƙa, a fayyace ko akasin haka, tare da wannan likitan. Manufar ambaton wannan likita shine yarda, yarda da kuma yaba da cikakken bincike da ayyukan ci gaba da masana kimiyyar da ke aiki akan wannan abu suka yi.
References
[1] Lilly :Sakamakon Tirzepatide Mataki na 3 Yana Nuna Mafi Girma A1C Da Rage Nauyin Jiki A Nau'in Ciwon sukari Na 2".Insider Kasuwanci.RTTNews.19 Oktoba 2021. An adana shi daga asali a ranar 28 ga Oktoba 2021. An dawo da 28 ga Oktoba 2021.
[2] Tirzepatide ya rage girman A1C da nauyin jiki a cikin mutanen da ke da ciwon sukari na 2 a cikin gwaji biyu na lokaci 3 daga shirin Lilly's SURPASS” (Latsa Latsawa) - ta hanyar PR Newswire.
[3] Kellaher, Colin (28 Afrilu 2022)."Eli Lilly's Tirzepatide Haɗu da Babban Mahimman Mahimman Ƙarshen Nazarin Kiba na Mataki na 3".MarketWatch.Dow Jones Newswires.An ajiye shi daga asali a ranar 29 ga Afrilu 2022. An dawo da 29 Afrilu 2022.
[4] Willard FS,Douros JD,Gabe MB,Shawalter AD,Wainscott DB,Suter TM, et al.(Satumba 2020)."Tirzepatide ne rashin daidaituwa da son zuciya dual GIP da GLP-1 agonist mai karɓa".JCI Insight.5 (17) .doi:10.1172/jci.injin.140532.PMC 7526454.PMID 32730231.
[5] Frederick MO, Boyse RA, Braden TM, Calvin JR, Campbell BM, Changi SM, et al.(2021)." .25 (7):1628–1636.
[6] Frías JP, Davies MJ, Rosenstock J, Pérez Manghi FC, Fernández Landó L, Bergman BK, et al. (Agusta 2021)." (2):385–6.doi:503/NEJMoa515.
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